Synthesis, Spectroscopic Characterization and Biological Studies of Metal Complexes

Basavaraj A. Kaloji1 and Kashinath G. Kanaje*

1Department of Chemistry, K C T Engineering College Kalaburagi-585104, Karnataka, INDIA.


A ligand (2-hydroxy-3-methoxyphenyl)(piperidin-1-yl)methylthiourea, was prepared by reacting with 4-hydroxy-3-methoxybenzaldehyde, piperidine and thiourea. Using the above ligand, the metal complexes of Cu(II), Co(II). Ni(II), Mn(II), Cd(II) and Hg(II) were prepared. The ligand and its metal complexes were characterized by physical methods such as elemental analysis, melting point, TLC and spectral method such as IR, 1H NMR, UV-Visible, ESR studies. For the complexes, molar conductivity and magnetic susceptibility were also been carried out. The electronic spectra and magnetic moment results proved that the complexes adopted octahedral geometry. The conductance measurement showed that the complexes are non electrolytes in nature. The synthesized ligand and its metal complexes were tested for their antifungal and antibacterial activity using standard drugs.

Keywords :Thiourea, Piperidine, ESR, UV-Visible and Microbial activity.