Preparation and Evaluation of Substituted 1-amino dibenzofuran Derivative as Antibacterial and Antifungal Agents

S. Syed Shafi1*, R. Subaash1, 2 and S. Senthilkumar3

1Department of Chemistry, Thiruvalluvar University, Serkkadu, Vellore, Tamilnadu, 632115, INDIA. 2Department of Chemistry, Arunai Engineering College, Tiruvannamalai, Tamilnadu,606603, INDIA. 3Department of chemistry, ArunaiCollegeof Engineering, Tiruvannamalai, Tamilnadu,606603, INDIA.


A chain of 1-amino dibenzo[b,d]furan acetamide derivatives were synthesized by reacting through1, 3-dinitrophenol, iodophenolwith 2-chloroacetyl chloride. To understand the chemical structures of the compound 1H NMR,13C NMR spectra were recorded. With the help of the LCMS test the mass of the synthesized compounds was estimated. The FTIR spectral analysis was employed to identify the functional groups present in the title compound. The in vitro antibacterial and antifungal activities of these compounds were also screened for industrial applications.

Keywords :1-nitro dibenzofuran derivatives;1-amino dibenzo[b,d]furan acetamide; biological activities.