Ternary Complex of Ni(II) Derived from Substituted Benzothiazole and Benzoimidazole : Synthesis and Biological Evaluation

Seema, Suman Kumari and Mamta Ranka

Department of Chemistry,
University of Rajasthan, Jaipur-302 004, INDIA.


Mixed ligand derived metal complexes have wide range of applications in medicinal and biological fields.1-2 Our present work report synthesis of novel ligands using 4-methylacetophenone with 2-aminobenzothiazole (L1) and 2-aminobenzimidazole (L2) respectively. Above synthesized ligands (L1, L2) were characterized by elemental analysis, molecular weight determination, magnetic moment measurements and various spectroscopic techniques (UV-VIS, FTIR, NMR etc.). Further metal salt of Ni(II) was allowed for complexation with synthesized ligands and characterized. On the basis of above studies a six coordinated octahedral geometry has been proposed for above complex (Ni L1 L2 Cl2. nH2O). Further, synthesized compounds were evaluated for biological activity against various bacterial and fungal strains and results were concluded. In continuation of our research work, attention is made to synthesize new biologically active compounds by greener methods also.

Keywords :Mixed ligand complex, spectroscopic techniques, 4-methylacetophenone, 2-aminobenzothiazole, 2-aminobenzimidazole.