Therapeutic Potential of Azadirachta indica (Neem) and Their Active Phytoconstituents against Diseases Prevention

Muhammad Jahangir Latif1, Syeda Mona Hassan1, Shahzad Sharif Mughal1*, Asma Aslam1, Muneeza Munir1, Nageena Shabbir1, Maryam Mushtaq1 and Sumaira Perveiz1

1Department of Chemistry, Lahore Garrison University, Sector C Phase 6 DHA Lahore, Punjab, PAKISTAN.


Neem (Azadirachta indica) is an important member of the Meliaceae family and its role as health-promoting effect is attributed to it is rich source of phytoconstituents. It has been widely used in Ayurvedic, Chinese and Unani medicines worldwide particularly in Indian Subcontinent in the prevention and treatment of various diseases. Earlier finding confirmed that neem and its phtoconstituents play a key role to scavenge free radical generation and prevention of disease pathogenesis. It is considered as safe medicinal plants and regulates the various biological processes without any adverse effect. In this current review, the role of Azadirachta indica is summarized in the prevention and treatment of diseases via the regulation of various physiological and biological pathways.

Keywords :Aflatoxin; spices; Fungal infestation; Azadirachta Indica; Aspergillus flavus.